The estimated incidence of NF2 is 1 in 33,000 people worldwide. Symptoms of the disease usually become apparent during puberty or early adulthood. The average age of onset is 18 to 24 years ...

In cases of inherited NF2, the severity is often similar between family members, and the type of mutation is therefore considered a major determinant of disease severity. Some symptoms of NF2 are ...

Neurofibromatosis, or NF ... “If you have someone with a very mild version of the disease and they don't have any internal tumors or don't have any tumors that become malignant, they can ...

Medically reviewed by Brigid Dwyer, MDMedically reviewed by Brigid Dwyer, MD Neurofibromatosis (NF) is a genetic neurological condition that is usually inherited. There are three types of ...

which includes what has been known an NF2 and schwannomatosis, while further classifying each type of schwannomatosis by the gene containing the disease-causing pathogenic variant. This change was ...

Selumetinib (Koselugo) significantly improved response rates in adults with neurofibromatosis type 1 (NF1) and symptomatic, ...

But the other, less common, types of the disease — NF2 and "Schwannomatosis" — can come with much more severe symptoms, like tumors that aren't just painful or itchy but also tend to more ...