The nuclear factor (NF)-κB, inhibitor of NF-κB (IκB) and IκB kinase (IKK) pathway is activated in response to various stimuli in many cell types. NF-κB is activated by many mechanisms ...

The yet-to-be peer-reviewed findings may help find new treatments for cancer and therapies to boost lifespan in humans, scientists say. Previous research has shown that the Greenland shark, which ...

F. Javier Rodríguez Baena, the first author of the article, explains, "We demonstrated that when we block Rela/NF-kB signaling in microglia, these cells begin to send signals to other immune ...

REC-3565 is a potential best-in-class MALT1 inhibitor for multiple hematology indications, designed to reduce the risk of hyperbilirubinemia, a common side effect of other MALT1 inhibitorsSalt Lake ...