Myotonia is a rare condition in which the muscles are unable to relax after they contract. This can affect muscles throughout the body and is caused by changes in the genetics of the individual ...

Today’s information comes to us from the NIH U.S. National Library of Medicine Genetics Home Reference. Myotonia congenita is a disorder that affects muscles used for movement. Beginning in ...

In 2012, a multi-centered international trial led by the same UCL research team successfully repurposed mexiletine—a sodium channel blocker—to treat non-dystrophic myotonia, demonstrating that ...

Did you know that certain medications can cause symptom of 'Myotonia'. Find these drugs listed on the page and be warned of similar symptoms as possible side-effects.

Again, if myotonia were purely a reflection of hypopolarization and hyperexcitability, as advocated by some authors, one might expect a worsening on repeated contractions, ...

Myotonia congenita is an inherited neuromuscular disorder. The characteristic of the disorder is the inability of muscles to quickly relax after a voluntary contraction. The condition is present ...

IN 1909, Steinert described a familial, chronic, slowly progressive disease characterized by visual and glandular disturbances combined with muscular atrophy. This has been called myotonia ...

Correction of Clcn1 alternative splicing reverses muscle fiber type transition in mice with myotonic dystrophy. Nature Communications , 2023; 14 (1) DOI: 10.1038/s41467-023-37619-1 Cite This Page : ...

Comedian Gilbert Gottfried, shown in a 2016 photo, died on Tuesday, April 12, from recurrent ventricular tachycardia due to myotonic dystrophy type II. Scott Roth Scott Roth/Invision/AP Comedian ...

Background A 56-year-old woman was referred to a neurogenetic clinic with a history of stiffness and transient weakness. A previous needle electromyogram had confirmed the presence of myotonia ...

The study, published in Lancet Neurology, detailed the "head-to-head" trial implemented by the researchers to test two drugs, mexiletine and lamotrigine, on people with the condition.