The study on mucins demonstrates how a long-time partnership between evolutionary biologists and dental researchers at UB is yielding new insights into genes and proteins that are also important to ...

Independent evolution of “orphan” mucins To investigate how orphan mucin genes evolved, the researchers trawled through the genomes of different species to pick out genes with PTS repeats, a reliable ...

The doubled regions, called "repeats," are key to a mucin's function, say University at Buffalo researchers Omer Gokcumen and Stefan Ruhl, the senior authors of the study, and Petar Pajic, the ...

A study of mucins, a protein in mucus, gives insight into how novel gene functions evolve. From slugs to saliva, mucus is responsible for making a lot of things slimy, but how did mucus evolve to be ...

The fact that the mucin adaptation keeps cropping up in so many animals means it’s a significant gene function that needs more investigation, says one of the study’s authors, biological ...

Details of the novel additive mechanism of mucin’s convergent evolution were published in the journal Science Advances (“ A mechanism of gene evolution generating mucin function”).

To answer that question, the researchers made two different synthetic mucins, also called mucin mimics, each with a different backbone. They gave one of the mimics a more compact backbone, which ...

Complex mucin gels have been shown to capture and hold biologically active molecules that might function as indicators of molecular or physical breach of the mucin layer and, following their ...

BUFFALO, N.Y. — From the slime coating slugs to the saliva in our mouths, many slippery bodily fluids contain mucus. So how did this marvel of biology evolve? In mammals, the answer is many times, and ...

Journal Science Advances DOI 10.1126/sciadv.abm8757 Article Title A mechanism of gene evolution generating mucin function Article Publication Date 26-Aug-2022 ...