Interestingly, stimulating the mPFC enhanced the rodents’ ability to wait but only when they did not know the food’s arrival time. These results suggest that serotonin in the mPFC affects the ...

Psilocybin, the psychoactive compound found in “magic” mushrooms, has shown promising antidepressant effects in both humans and rodent models. These therapeutic effects are thought to involve ...

Adolescent diets high in fat and sugar disrupt the development of the prefrontal cortex and hippocampus, impacting cognition, ...

Rodent medial prefrontal cortex is not crucial for an active place avoidance task requiring cognitive control evidenced by hippocampal activity that purposefully alternates between task-relevant and ...

In humans, the medial prefrontal cortex (mPFC) plays an important role in moderation of stress and also in social cognition, so the researchers theorized that the same may be true for mice.

In contrast, high-ranking mice have a weaker 'reward' pathway and a stronger 'control' pathway—like driving a car with effective brakes and controlled acceleration—helping them resist drug ...

Researchers studied mice brains, focusing on the deeper layers of the lateral entorhinal cortex, where they discovered specialized, item-outcome neurons essential for learning. Odors are critical ...