Researchers have reversed lung fibrosis in a mouse model of idiopathic pulmonary fibrosis. Mice were given bleomycin for 12 days to establish lung fibrosis, and then treated daily until 21 days ...

Using lung lavage, they isolated macrophages from people with IPF. They found a marked increase in the macrophage mitochondrial protein Bcl-2 — a regulator of apoptosis — as compared to lung ...

Acquired pulmonary alveolar proteinosis has been treated successfully since the early 1960s by whole-lung lavage, and this procedure remains the standard of care today. 109–113 Although it has ...

Adenovirus vectors (Ad) are widely used in gene therapy studies, including those aimed at treating cystic fibrosis lung disease. Various approaches have been investigated to blunt the host immune ...

Our research employs a variety of experimental and analytical technologies, utilizing animal models such as the smoke mouse model of COPD, lung bacterial infection mouse model, lung cancer mouse model ...

Researchers have reversed lung fibrosis in a mouse model of idiopathic pulmonary fibrosis, as reported in a study published in the journal Cell Death and Differentiation. Mice were given bleomycin ...

Using a four-dimensional microscopy technique, researchers at Vanderbilt University and Vanderbilt University Medical Center ...

A better understanding of inflammation and lung immunity over the past two decades has led to new, innovative treatments for asthma, including biologic therapies. This is especially true for a ...

Using a novel mouse lung transplant model of chronic rejection their laboratory ... which started from the bedside when we examined the lavage fluid from our lung transplant recipients, ...

St. Louis, July 11, 2006 — Lung transplants have been performed successfully for more than 20 years in humans but never before in mice – until now. Surgeons at Washington University School of ...

Using video microscopy in the living mouse lung, UC San Francisco scientists have revealed that the lungs play a previously unrecognized role in blood production. As reported online March 22, 2017, in ...