Patients with chronic lymphocytic leukemia (CLL) had significantly lower monocyte-to-lymphocyte ratio values compared with ...

On the other hand, disturbed monocyte function is associated with "immune paralysis". In this condition, the immune system's ability to fight off invaders such as viruses and bacteria is inhibited.

Monocytes have been subdivided into 3 groups, based on their relative expression of CD14 and CD16. The most abundant subgroup is referred to as the classical subgroup, which are CD14 + and CD16 −.

Liver failure syndromes are characterized by a dysregulated immune response leading to immune paralysis. Adrenomedullin (ADM) ...

Liver failure syndromes are characterised by a dysregulated immune response leading to immune paralysis. Adrenomedullin (ADM) ...

Understanding how monocyte functions are regulated is critical to prevent these harmful outcomes. We reveal platelets’ vital role in the pro-inflammatory cytokine responses of human monocytes.” ...

When MCSF- or GMCSF-treated monocytes were co-cultured with T-cells, MCSF-treated monocytes suppressed T-cell cytokine secretion and induced FoxP3 expression. Conclusions: CD14+CD16-HLADR low ...

On the other hand, disturbed monocyte function is associated with "immune paralysis". In this condition, the immune system's ability to fight off invaders such as viruses and bacteria is inhibited.

Dr. Dobbs’ research interests include innate immunity to malaria and childhood infections of global health significance. She is currently principal investigator of a career development award studying ...