M phase (mitosis): Mitosis involves the segregation of the sister chromatids. A structure of protein filaments called the mitotic spindle hooks on to the centromere and begins to contract.

University of Warwick. (2014, February 18). Mitosis mystery solved as role of key protein is confirmed. ScienceDaily. Retrieved June 2, 2025 from www.sciencedaily.com / releases / 2014 / 02 ...

I describe the different ways in which the vesicular coat protein clathrin and other components of the clathrin-mediated endocytosis (CME) machinery are proposed to function during mitosis.

Gastric cancer, which is the fifth most frequent cancer globally and the third most frequent cause of cancer-related deaths, can be managed relatively well with existing therapies. Advanced gastric ...

This study clarifies how this works. The Mitotic Stopwatch Complex consists of 3 proteins: p53 binding protein 1, USP28 and p53 protein itself. These proteins only interact during unusually longer ...

The high levels, while artificial, also point to BubR1's uniqueness. It is the only mitotic protein known that can be overexpressed without causing problems with the division of the cell.

They found that mitotic stopwatch complex consists of three proteins, p53 binding protein 1, USP28 and p53 itself. These proteins only interact during an unusually long mitosis, and during this ...

Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert ...

From this, we may be able to disrupt the function of the protein complex in dividing cells and inhibit the sharing of chromosomes during mitosis, causing the death of cancerous cells. The research ...

Researchers from Warwick Medical School have discovered the key role of a protein in shutting down endocytosis during mitosis, answering a question that has evaded scientists for half a century.