As a result, ROS from overactive mitochondria are frequently cited as a source of DNA damage. Despite this longstanding belief, few studies have explicitly demonstrated this linkage. Tobias Dansen, a ...

Mitochondrial DNA (mtDNA) is actively removed during spermatogenesis in a conserved process that enforces the uniparental ...

Typically, humans inherit mitochondria and mitochondrial DNA from their mothers only. But using sequencing data from the mitochondrial genomes of members from three unrelated families, researchers ...

New research at the University of Alberta may make it easier to diagnose serious diseases that disrupt the body's energy ...

Commonly used to preserve or fix tissues for staining, formaldehyde has the ... of the maxicircle is comparable in size to the mitochondrial DNA of other eukaryotic cells, scientists assumed ...

Mitochondria also contain DNA, and they show similar patterns of ... Fixation and electron staining reactions. Journal of Cell Biology 19, 593–611 (1963) ———. Intramitochondrial fibers ...

“We disrupt the membrane so mitochondria cannot work functionally to produce energy or work as a signaling hub. This causes programmed cell death followed by DNA damage – our investigations ...