can stimulate both apoptosis and autophagy. Organellar stress that affects mitochondria and the endoplasmic reticulum can induce a specific autophagic response that leads to the removal of damaged ...

The researchers confirmed that the increased production of hydrogen peroxide did not impede the function of mitochondria. They investigated a form of apoptosis caused by hydroxy radicals formed in the ...

Mitochondria are critical for cellular homeostasis, regulating bioenergetics, redox balance, Ca2+ signaling, and cell death. Mitochondrial Ca2+ (Ca2+mito) plays a dual role in physiological processes ...

Rotenone, an inhibitor of the mitochondrial electron transport chain, prevented ROS generation and apoptosis in response to edelfosine in S cerevisiae. α-Tocopherol abrogated the edelfosine ...

Our findings demonstrate that mitochondria dynamics do not regulate apoptosis activation in C. elegans and reveal distinct roles for drp-1 and fis-2 as mediators of cell-death execution downstream of ...

Mitochondria are crucial organelles for cellular homeostasis, regulating processes such as ATP production, reactive oxygen species (ROS) management and Ca2+ signaling.