New-onset migraine was noted in ten patients. ASD: Atrial septal defect; NA: Not assessed; NR: Not reported; PFO: Patent foramen ovale. Box 1. The 'embolic' hypothesis. The following arguments ...

The relationship between patent foramen ovale and migraine is a hotly debated issue. Conflicting data on the association or independence of these conditions have been reported by various study ...

Migraine with aura is the most prominent individual risk factor for unexplained stroke in adults younger than 50 years, particularly in women and in those with patent foramen ovale (PFO), a new ...

Traditional risk factors were more strongly associated with stroke in men and women without a PFO. In contrast, nontraditional risk factors, such as blood clots in the veins, migraine with aura ...

Non-traditional factors included migraines with aura, kidney disease, liver disease, blood disorders, autoimmune diseases and cancer. Results showed that: In people without the PFO heart defect ...

But overall, migraine with aura, or sensory disturbances such as flashes of light, was the leading nontraditional cause linked to cryptogenic strokes, especially among women and people with a PFO.