As the tissue macrophages of the CNS, microglia are critically involved in diseases of the CNS. However, it remains unknown what controls their maturation and activation under homeostatic conditions.

Microglia, cells thought restricted to central nervous system, are redefined in new study. ScienceDaily . Retrieved June 2, 2025 from www.sciencedaily.com / releases / 2019 / 04 / 190404161007.htm ...

Major depressive disorder affects hundreds of millions worldwide, but a key to understanding its origins may lie in the brain ...

The main immune cells in the Central Nervous System (CNS) are called microglia and can be considered the brain's resident macrophages. They are, therefore, in charge of triggering inflammation in ...

Microglia are important immune cells in the central nervous system (CNS) that play critical roles in CNS function and dysfunction." Bo Peng, Professor, Institute for Translational Brain Research ...

Rather than simply reacting to CNS injury, infection, or pathology, emerging lines of evidence indicate that microglia sculpt the structure of the CNS, refine neuronal circuitry and network ...

Many of the risk genes for Alzheimer's point toward a central role of microglia, the macrophage cells that act as one of the main methods of immune defense in the central nervous system.

Microglia have counterparts called macrophages that serve similar function outside the CNS in the peripheral nervous system (PNS), the region that contains most of the sensory and motor nerves.

Microglia, also known as macrophages of the central nervous system (CNS), are specialized immune cells vital for brain health and injury response. Traditionally, microglia were thought to be absent ...

Multiple sclerosis (MS) is one of the most progressive autoimmune diseases that affect the central nervous system where the immune system attacks the myelin sheath that covers the nerve fibers and ...

Taking the research one step further, the team homed in on what mechanism the gut bacteria could be using to enhance the activity of microglia in the CNS and brain. Experiments revealed one ...