Learn about our Editorial Policies. “It appears as though a significant fraction of cell death in neurogenic regions is not due to intrinsic death of the cells but rather is a result of the microglia ...

Interestingly, the authors showed that microglia and infiltrating monocytes isolated from the active border of lesions in the CNS of patients with multiple sclerosis expressed higher levels of ...

The second type of mouse is deficient in CCR2 (CCR2 −/−), a receptor involved in chemotaxis that is expressed by microglia and monocytes, two kinds of immune cells that can be found in the brain.

This destructive act is important for the developing brain. The microglia prune away weak or unwanted connections, allowing more productive ones to become stronger. Without this “synaptic pruning,” a ...

Microglia are brain-resident macrophages playing pivotal roles in CNS development and homeostasis. Yet, the cellular and molecular basis governing microglia maintenance ...