In the Protein Engineering and Evolution Unit's latest publication in Nucleic Acids Research, the team presents an engineered RNA methyltransferase, which can be used to study the role of RNA ...

Figure 3: The Dnmt1-interacting region of HDAC1 associates with methyltransferase activity. We transiently transfected 293T cells in culture dishes (15-cm diameter) with pCMV-Myc-Dnmt1 (20 μg ...

Bacteriophages, the most abundant life form on Earth, infect bacterial cells and influence the structure of the microbial community. To fend off phage attacks, bacteria have evolved their own defense ...

PRMT1, arginine methyltransferase 1; CBP, CREB binding protein; HDAC1, histone deacetylase 1; SIRT3, sirtuin 3; HAT1, histone acetyltransferase 1. Chronic hepatitis B virus (HBV) infection continues ...

Researchers from the Skoltech Laboratory for Metagenome Analysis, which is led by Assistant Professor Artem Isaev, and their colleagues from the United Kingdom have studied the BREX methyltransferase ...