DNA methylation is one of several epigenetic ... DNA also form complexes with the proteins involved in deacetylation of histones. Therefore, when DNA is methylated, nearby histones are ...

Methylation is one of the more prevalent chemical modifications that histones undergo. Researchers have previously found that the methylation of one particular location, lysine-4, on histone H3 ...

Researchers discovered a molecular timer that gets activated in the first days of pregnancy and influences when mice give ...

The following is a summary of “Histone Modifications and DNA Methylation in Psoriasis: A Cellular Perspective,” published in ...

Some patterns of histone methylation are linked to human gene activation, and other patterns are linked to gene repression. By combining chromatin immunoprecipitation with new Solexa 1G sequencing ...

Over the course of pregnancy, levels of methylation on these histones fade in a slow and steady way, eventually reaching low enough levels that the nearby genes—related to pregnancy events like ...

Modifying histones can affect transcription by altering the structure ... represent a more complex and diverse mechanism to affect gene transcription than DNA methylation. In fact, one effect of DNA ...

that site is a glutamine unit near the end of the tail on H3 histones called H3Q5. Right next to that glutamine is a lysine, H3K4, that is a common site for methylation. Methylation at H3K4 ...

Epigenetic alterations have emerged as critical factors in the pathogenesis of brain cancer, particularly gliomas. This article explores the impact of organochlorine pesticides (OCPs) on the ...