most notably in macrophage foam cells, that is strongly correlated with atherosclerosis. Macrophages mediate a limited-specificity immune response that includes recognition of ‘foreign’ lipid ...

In May Nature Medicine, Liza Makowski and colleagues from Harvard School of Public Health, Boston, demonstrate that aP2 is also expressed in macrophages and has a role in the development of ...

Here I will primarily discuss a key immune cell—the macrophage—and its involvement in lipotoxic responses during atherosclerosis, focusing on its role in pathogenesis through alterations in ...

Interfering in the downstream effects of pyroptosis, either by blocking certain molecules or destroying macrophages, stopped cytokine release syndrome from occurring in mice. “The experiments need to ...