most notably in macrophage foam cells, that is strongly correlated with atherosclerosis. Macrophages mediate a limited-specificity immune response that includes recognition of ‘foreign’ lipid ...

Here I will primarily discuss a key immune cell—the macrophage—and its involvement in lipotoxic responses during atherosclerosis, focusing on its role in pathogenesis through alterations in ...

X. Liao et al., “Macrophage autophagy plays a protective role in advanced atherosclerosis,” Cell Metabolism, 15:545-53, 2012. Atherosclerotic plaques can prompt heart attacks and strokes when ...

Interfering in the downstream effects of pyroptosis, either by blocking certain molecules or destroying macrophages, stopped cytokine release syndrome from occurring in mice. “The experiments need to ...