Cancer biologist Linda Penn of the Ontario Cancer Institute and the University of Toronto in Canada, who was not involved in the study, noted that Myc’s apparent broad role in aging comes as a ...

Inhibiting RMB42 disrupted production of Myc proteins in pancreatic cancer cells. This approach could curtail the growth of several cancer types. A review paper published last year in European ...

Expression of the cell cycle inhibitor p15 INK4b is suppressed by the Myc oncoprotein and induced by transforming growth factor-β (TGF-β). The transcription factor Miz-1 activates the Ink4b ...