The crystal structure of human matrix metalloproteinase type-2 (MMP-2), a key target for several anticancer therapies currently in trials, has now been solved to a 2.8Å resolution (Science 284 ...

The primary aim of this study was to examine resting levels of MMP-2 and -9, which are involved in the degradation of several ECM components, to assess whether sex difference exist. Additionally, we ...

Our findings show that micromolar EGCG inhibits tumor cell invasion and directly suppresses the activity of MMP-2 and MMP-9, two of the proteases most frequently overexpressed in cancer and ...

The risk of some skin cancers, including squamous cell carcinoma, basal cell carcinoma, and non-melanoma skin cancer, was ...