CD8 + T cells can recognize and then kill HIV-infected cells following the presentation of fragments of viral proteins (epitopes) in the peptide-binding groove of MHC class I molecules on the ...

Viral protein is made intracellularly and the protein is processed via the endogenous MHC class I pathway ... cells and transcribed in the nucleus (1). The single stranded mRNA (2) is translated ...

CD8-positive T cells are a critical subpopulation of MHC class I-restricted T cell and ... Here authors show that NKG7, a lysosomal protein specifically expressed in CD8 + T cells, inhibits ...

While it's known that major histocompatibility complex class I (MHC ... with cysteines: protein building blocks found within peptide antigens displayed on the surface of MHC-I molecules.