Pregabalin binds with high affinity to the alpha2-delta site ... max 660mg/day if insufficient relief after 2–4wks. Conversion from Lyrica capsules, oral soln: see full labeling.

Richard B. Silverman’s 1988 discovery led to the creation of blockbuster drug Lyrica. The initial research began in 1988 in Northwestern professor Richard B. Silverman’s chemistry lab. Silverman and a ...