The liver has a unique structure, especially at the level of individual cells. Hepatocytes, the main liver cells, release ...

To curtail this reliance and provide an improved model for predicting drugs' side effects, scientists have been engineering liver tissue in the lab. But so far, they haven't achieved the complex ...

This is why liver models are increasingly being developed in the lab as platforms for drug screening. However, existing models so far lack both the complex micro-architecture and diverse cell makeup ...

create functional tissue to model liver disease ... It's also still unclear if liver cells grown in the lab function precisely like those in a person, a challenge for all lab-grown human livers ...

Scientists develop most sophisticated human liver model in the laboratory that better mimics foetal development and function of the human liver, revealed lead researcher Shay Soker, Professor at ...

This finding is significant if the model is to be used for screening of potential drugs for the treatment of NAFLD. "Our multicellular liver-on-a-chip system is a laboratory model that is more ...

Until now, scientists working on hepatitis C vaccine design have been hampered by the lack of an animal model or a culture ... way it would infect liver cells in the human body. Khetani and Alexander ...

The liver has a unique structure, especially at the level of individual cells. Hepatocytes, the main liver cells, release bile into tiny channels called bile canaliculi, which drain into the bile duct ...

Models provide highly relevant species-specific data, predict in vivo drug clearance/transport, and support preclinical ...

Because of this unique architecture, liver disease investigation has been limited by the lack of lab-grown models that accurately show how the disease progresses, as it is challenging to recreate ...

Because of this unique architecture, liver disease investigation has been limited by the lack of lab-grown models that accurately show how the disease progresses, as it is challenging to recreate the ...