In order to determine whether the presence of lipid-laden macrophages in tracheal aspirates is useful diagnostically we prospectively evaluated samples stained with Oil-Red-O in ventilator ...

We have established a cDNA microarray platform for use in research focused on atherosclerosis and heart disease. Our objective is the elucidation of signalling pathways with an impact on ...

Our more recent observations indicate that certain oxidized lipids themselves are also recognized and endocytized through macrophage receptors. We previously showed that the adduct formed by the ...

Antibodies, which recognize viruses and proteins that the body has encountered before, have long gotten most of the credit ...

Research identifies how viral respiratory infection damages macrophages and suggests treatment with a pre-existing FDA approved drug.

More information: Dedipya Yelamanchili et al, HDL-free cholesterol influx into macrophages and transfer to LDL correlate with HDL-free cholesterol content, Journal of Lipid Research (2024).

Iron-dependent ferroptosis, a non-apoptotic cell death mechanism, is gaining attention for its role in immune suppression.

The Active Lives of Lipid Metabolites A cell's phospholipid membrane molecules can be broken down to form five classes of signaling lipid metabolites, one of which are the lysophospholipids. These ...

Caption Influenza infections are characterized by massive influx of monocytes/macrophages in the lungs. Although it is required to eliminate the virus, excessive inflammation contributes to the ...

lycopene Decrease cholesterol crystals, LDL phospholipids, ox-LDL, APO-B and seven ketosteroids that activate PRR. Omega 3 fatty acids and statins Decrease modified LDL macrophage uptake by ...