New genetics research by scientists at the University of Copenhagen suggests that leptin plays a stronger role in controlling the weight of children than in adults. Young children of African ...

That “stuff,” Mehal says, could be any number of things from exercise to growth in puberty to conceiving a child. Low levels of leptin, on the other hand, are part of the complex hormonal ...

In this effort, the research team were presented with two children, one a 14-year-old boy, the other a 2-year-old girl. Both were suffering from obesity and hyperphagia, in which the desire to eat ...

Obese children have high leptin levels, and these may play a role in their earlier onset of puberty. Leptin receptors have been identified in the hypothalamus, gonadotrope cells of the anterior ...

Here, we characterize two novel homozygous leptin variants that yielded antagonistic proteins in two unrelated children with intense hyperphagia, severe obesity, and high circulating levels of leptin.

Two children who experienced intense, insatiable hunger that drove them to overeat have rare, never-before-seen genetic mutations that interfere with leptin, a key hormone that helps tell the body ...

The circulating leptin levels in our patient were within the range of levels found in other children with extreme obesity not related to leptin deficiency. 7 The secreted amounts of mutant leptin ...

OBJECTIVE: To study the relationships between physical activity and plasma leptin levels in children from a population-based study, taking into account puberty stages. DESIGN: Subjects were part ...

In addition, healthy leptin levels can boost your chances of getting pregnant or carrying a child. It sends a signal to your brain that it’s OK to ovulate and prepare the uterus for a baby.

Children with Down syndrome are more likely than their unaffected siblings to have higher levels of a hormone associated with obesity, according to pediatric researchers. The hormone, leptin ...

Celastrol increases the brain's sensitivity to leptin, the hormone that signals ... a study led by Umut Ozcan, MD, at Boston Children's Hospital finally solves the mystery. Ozcan's team initially ...

Leptin is a hormone that reduces appetite and ... circulation are lowest early in the morning and rise upon waking. Children exposed to adversity show a blunted cortisol-awakening response ...