Study: Low-Density Lipoprotein Receptor (LDLR) Is Involved in Internalization of Lentiviral Particles Pseudotyped with SARS-CoV-2 Spike Protein in Ocular Cells. Image Credit: PHOTOCREOMichal ...

Disruptions in LDLR function or apoB100 mutations, as seen in FH, lead to low-density lipoprotein cholesterol (LDL-C) accumulation, triggering atherosclerosis. 3-hydroxy-3-methylglutaryl-coenzyme ...

We want to determine if and to what extent LDLR-targeted anti-cancer drug and prodrug nanoparticles can have activity in brain cancer, both injected intravenously and/or as post-surgical deposits." ...