“These data implicate LDHA as an important metabolic protein in the immune response in human tuberculosis lesions,” said Adrie Steyn, Ph.D., senior author of the research. Knowing that NADH/NAD+ ...

Glycolysis is the pathway that converts glucose ... LDH has of four subunits, a mix of LDHA and LDHB subunits. When LDH is made mostly of LDHA subunits, a subunit that is predominantly expressed ...

CHK-336 is an oral small molecule lactate dehydrogenase A (LDHA) inhibitor with liver-targeted tissue distribution being developed for the treatment of patients with primary hyperoxaluria (PH ...