CMR scans may reveal lamin heart disease prognostic biomarkers, enabling clinicians to better predict which patients are most ...

Harvard University researchers at the Broad Institute report that expansion in situ genome sequencing (ExIGS) linked nuclear abnormalities to hotspots of aberrant chromatin regulation, potentially ...

Nucleoplasmic lamin C rapidly accumulates at sites of nuclear envelope rupture with BAF and cGAS. Journal of Cell Biology , 2022; 221 (12) DOI: 10.1083/jcb.202201024 Cite This Page : ...

For instance, they found that rapid repair did not occur or was weakened in lamin C mutants, namely R435C, R471C, R527H, A529V, and K542N, compared to wild type (control) ...