Long-term potentiation (LTP) of synaptic transmission is thought to be an important cellular mechanism underlying memory formation. A widely accepted model posits that LTP requires the cytoplasmic ...

Commentary Published: 01 July 2005 Postsynaptic depolarization requirements for LTP and LTD: a critique of spike timing-dependent plasticity John Lisman & Nelson Spruston Nature Neuroscience 8 ...