Children born to obese mothers are at higher risk of developing metabolic disorders, even if they follow a healthy diet ...

Children born to obese mothers are at higher risk of developing metabolic disorders, even if they follow a healthy diet ...

Obese liver disease may start before birth. A new study shows how maternal weight reprograms liver cells in offspring.

This is a useful study in the role of CHI3L1 in Kupffer cells, the macrophages of the liver, showing that CHI3L1 alters glucose regulation in obesity. Specifically, Chi3l1 protects glucose-dependent ...

If Kupffer cells (KCs), a specific kind of immune cells found in the liver, become impaired by tissue scarring, immune cells originating in the bone marrow flow to the organ, ...

LPS-stimulated mouse Kupffer cells on PRX surfaces with high mobility had smaller areas of spread than those on PRX surfaces with low mobility, whereas the cells showed higher expression levels of ...

Using single-cell RNA sequencing of murine macrophages, a distinct and highly susceptible Kupffer cell subtype, Clec4F + /CD206 +, emerged, with heme oxygenase 1 (HMOX-1) playing a pivotal role.