The c-Kit (CD117), receptor tyrosine kinase (RTK), and its ligand stem cell factor (SCF) are necessary for the development of embryos and the progression of human cancer. In gastrointestinal ...

Arcus Biosciences Inc. has disclosed mast/stem cell growth factor receptor Kit (KIT; c-Kit; CD117) inhibitors reported to be useful for the treatment of cancer, allergy, autoimmune, inflammatory, ...