Aurora-A kinase (AurA) is an enzyme that is hyperactive in many cancers and drives tumor cell proliferation. Several AurA inhibitors are currently being tested in clinical trials to see if they ...

The Aurora A kinase may contribute to polycystic kidney disease (PKD) by inactivating a key calcium channel in kidney cells, according to a new study. The Aurora A kinase may contribute to ...

Aurora-A kinase (AurA) is an enzyme that is hyperactive in many cancers and drives tumor cell proliferation. Several AurA inhibitors are currently being tested in clinical trials to see if they ...

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Aurora kinase A (also called STK15 and BTAK) is overexpressed in many human cancers. Ectopic overexpression of aurora kinase A in mammalian cells induces centrosome amplification, chromosome ...

We undertook this study to investigate these issues and present data to demonstrate, for the first time, that RASSF1A is phosphorylated by a mitotic kinase named Aurora-A. We also present evidence ...

DUBLIN--(BUSINESS WIRE)--The "Aurora Kinase B - Pipeline Review, H2 2018" drug pipelines has been added to ResearchAndMarkets.com's offering. Aurora Kinase B (Aurora 1 or Aurora And IPL1 Like ...

Aurora A overexpression correlates with poor prognosis and is considered a therapeutic target for cancer treatments, although the clinical development of Aurora kinase inhibitors has been so far ...

The company is also developing selective degraders of Aurora A kinase for treating aggressive pediatric cancers, illustrating a multifaceted approach to combating difficult-to-treat malignancies.

PHILADELPHIA, PA. (September 7, 2010)—Aurora-A kinase (AurA) is an enzyme that is hyperactive in many cancers and drives tumor cell proliferation. Several AurA inhibitors are currently being ...