Small immune complexes (SICs) are thought to cause kidney damage by inducing type III hypersensitivity reactions, but the mechanisms involved are unclear. New findings show that macrophages ...

Researchers have found that, during acute kidney injury in a mouse model, the kidney-resident macrophages are reprogrammed to a developmental state, resembling these same cells when they are found ...

Scientists have achieved an unprecedented look into how the human immune system attacks a transplanted pig kidney, using ...

BIRMINGHAM, Ala. – Macrophages are immune cells that engulf and digest pathogens, cancer cells or cellular debris. The kidneys — like other tissues in the body — contain kidney resident ...

Understanding the possible healing role for these macrophages after kidney damage may be crucial to helping treat patients who suffer acute kidney injury. Skip to content. Menu.

George’s study, "Resident macrophage subpopulations occupy distinct microenvironments in the kidney," was recently published in JCI Insight. The team in George’s lab studies the role of immune cells ...

Macrophages can also alter the kidney microenvironment through interactions with endothelial cells, immune cells, fibroblasts, and tubular epithelial cells (TECs).

And it could not be better timed—the first US-based clinical trials of pig kidney transplantation into living humans begin ...

During development in the womb, immune cells called macrophages go to the kidneys, and they remain there for life. Understanding the possible healing role for these macrophages after kidney damage may ...