T helper 17 (Th17) cells generate the pro-inflammatory cytokine interleukin-17 (IL17/IL17A). IL17 has been a target for a variety of therapeutic monoclonal antibodies and inhibitors to treat ...

Cite this: Functional Interleukin-17 Receptor A is Expressed in Central Nervous System Glia and Upregulated in Experimental Autoimmune Encephalomyelitis - Medscape - Apr 01, 2009. 1 Department of ...

Japanese researchers now demonstrate for the first time that the interleukin (IL)-23–IL-17 axis is essential for brain inflammation after stroke. “Macrophages infiltrating the site produce IL ...

Exposure to TNF inhibitors was linked to a reduced risk for cardiovascular events among patients with AS; the impact of IL-17 inhibitors was less clear.