Organoids are made to model human organs and are promising for research and therapy, but there are limitations to their ...

2006). Using DNA microarrays, these investigators examined changes in gene expression at a global level in different cell types. In looking for a signature of hypoxia, the researchers compared ...

Ubiquinone, a metabolite critical to generating energy in cells, has long been thought to be the only mitochondrial electron transport chain carrier in mammals. Although other electron transporters ...

Increased dietary folic acid intake may lead to adverse health effects, including inflammation and neurotoxicity, ...

EPAS1-driven adaptation mechanisms enable tumor cells to proliferate under hypoxia and similarly, allow high-altitude ...

Yet for decades the precise workings were largely a mystery. Scientists knew that in low oxygen situations, or hypoxia, cells trigger a cascade of physiological events to restore oxygen ...

By lowering the media volume, and thus increasing the pericellular oxygen, Tan observed lowered hypoxia signaling and transcriptional rewiring that recapitulated a healthier adipocyte cell model.

Chemically restoring intestinal gut hypoxia could deter fungal blooms ... Revvity Inc. Singleron Biotechnologies today announced the launch of MobiuSCOPE, a single cell RNA sequencing kit that ...