5-Prime | The Histone Code Courtesy of IMP/TKadletz What is the histone code? Different chemical marks, such as acetylation, methylation, or phosphorylation, are made to numerous residues on the ...

Out of these observations was born the 'histone code hypothesis', which states that "distinct histone modifications, on one or more N-terminal tails, act sequentially or in combination to form a ...

The histone code hypothesis posits that distinct combinations of histone modifications can recruit chromatin-modifying enzymes and exert epigenetic control over heterochromatin assembly. In the March ...

The presence of specific histone codes can either enhance or repress gene expression, thereby affecting the activation state of HSCs and contributing to liver fibrosis.

Histone-based predictors were compared to DNA methylation-based predictors, with the study noting the impact of differences in sample size and dataset distributions on the comparison.

The findings are published in Science in an article titled, “ Nutrient-driven histone code determines exhausted CD8+ T cell fates,” and may lead to new therapies that target these nutrient ...

A new study has decoded how pea plants respond to salt stress through precise epigenetic reprogramming. Researchers created the first genome-wide map of four major histone modifications—H3K4me3 ...

The presence of specific histone codes can either enhance or repress gene expression, thereby affecting the activation state of HSCs and contributing to liver fibrosis.

Cite this: Breaking the Histone Code With Quantitative Mass Spectrometry - Medscape - Oct 01, 2011.