This review highlights how air pollution and occupational inhalation exposures may contribute to neurodegenerative disorders ...

Researchers are beginning to unpick the intricate molecular choreography that ensures faithful transmission of genetic and ...

Centromeres, specialized regions located at the center of chromosomes, are critical for ensuring proper cell division. During ...

The expression and/or function of histone deacetylases (HDACs) is often perturbed in cancer, neurological syndromes and immune disorders. HDACs can be effectively targeted using small-molecule ...

Epigenetics is an exciting new field of research into heritable changes of gene expression, acting through histone modifications and deoxyribonucleic acid (DNA) methylation, which occur without ...

Each spool is made of eight histone proteins and is encircled by just 147 of the human genome’s more than 3 billion base pairs, meaning each cell needs more than 163 million histones to hold all ...

BASF SE BASFY has started the registration of its new fungicide innovation, Adapzo Active, the industry’s first histone ...

The basic unit of chromatin organization is the histone, a protein complex around which DNA is wrapped to form a nucleosome. Histone proteins can be modified at defined amino acid residues by ...

We asked whether there is a link between the severity of disease and the reduction in histone deacetylase (HDAC) activity in the peripheral lung tissue of patients with COPD of varying severity.

Histone modification is an epigenetic mechanism that regulates gene expression by altering chromatin structure and DNA accessibility for transcription. Histone modification is regulated by various ...

When attached to specific amino acid side chains on a histone's tail, these chemical tags recruit proteins that change the local chromatin structure and, consequently, the accessibility of genomic ...

The cover art theme is "the weight of a histone." This visual serves as a rodent metaphor for Atlas, a Titan from Greek mythology who was condemned to carry heaven on his shoulders. The cover ...