DNA in the human Herpes simplex virus type 1 (HSV-1) capsid is packaged to a tight density. This leads to tens of atmospheres of internal pressure responsible for the delivery of the herpes genome ...

HSV-1 is a large virus that infects the mucous membranes of the mouth and genitals, causing life-long latent infections. The virus is composed of three layers—a capsid that contains the viral ...

The capsids of HSV-1 and HSV-2 are not just protective shells ... Understanding the structure of the capsid could be the key to stopping a viral spread. “A clear understanding of the structure ...

ONCR-719 is a novel, armed oncolytic HSV-1 vector engineered with targeted entry via EGFR/EGFRvIII and expresses four immunomodulatory payloads designed to reverse GBM’s immunosuppressive tumor ...

New insights into HIV-1 capsid disruption open doors for novel therapies Sven Eyckerman: "We noticed that incoming viruses were being lured into structures that resembled nuclear pores.

GSK has abandoned its clinical-stage vaccine for herpes simplex virus (HSV) after a disappointing phase 1/2 trial, ceding the ground to mRNA shots in development at Moderna and BioNTech.

HSV-1 is a large virus that infects the mucous membranes of the mouth and genitals, causing life-long latent infections. The virus is composed of three layers – a capsid that contains the viral ...