This article presents a simple and systematic approach to HPLC method development, beginning with sample preparation and finishing with practical analytical method validation. The wide variety of ...

This review highlights the high performance liquid chromatography (HPLC), mass spectrometry (MS), chromatography data systems ...

Learn how to set up and run HPLC analysis with full understanding of all the method parameters such as the column, the mobile phase, the instrumentation, and sample preparation, and how to interpret ...

Based on the instructor’s extensive experience in the laboratory supporting pharmaceutical and bioanalytical method development, those attending this course will gain the practical skills needed to ...

Many people use high performance liquid chromatography, yet very few understand how they work. HPLC seems like a complicated combination of motors, gears, pressures, flows, chemistry, physics and ...

The path from HPLC to UPLC is not entirely without difficulty as many companies have HPLC-based methods filed with regulatory agencies, particularly those used in quality control departments ...

However, a key challenge in highly regulated laboratories is when scientists must switch from one HPLC system to another, or exchange methods between different labs and sites. The process of ...

Transferring a method from a legacy HPLC instrument to a new HPLC system can be challenging. Differences in system characteristics, including dwell volume and or gradient delay, can produce retention ...

Why are stability-indicating methods important in pharmaceutical analysis? The stability-indicating assay is perhaps the single application of HPLC that has the most impact. It is the method used ...