Corticosteroid therapy must be tapered because of its interactions with the hypothalamic-pituitary-adrenocortical (HPA) axis. The hypothalamus secretes corticotropin releasing factor, which acts ...

Individuals with type 2 diabetes mellitus (DM) can have hypothalamic–pituitary–adrenal (HPA) axis dysfunction and cognitive impairment. Bruehl et al. sought to determine whether HPA ...

At six months postpartum, infant cortisol levels were collected before and after a mildly stressful laboratory task to see how their hypothalamic-pituitary-adrenal system, or HPA axis, responded ...

Adrenal steroidogenesis is under the control of the hypothalamic–pituitary–adrenal (HPA) axis. Furthermore, metabolic factors including insulin and obesity-related signals may play a role in ...

Research Interests: Neurobiology of psychological stress and stress adaptation; Hypothalamic-pituitary-adrenal (HPA) axis regulation; Stress and learning-dependent hippocampal immediate early gene ...

Avoid prolonged use or on large areas. Use lowest effective dose. Monitor for HPA axis suppression; avoid abrupt cessation if used for chronic conditions. Discontinue if infection persists or ...

Discontinue or reduce frequency, dose, or potency if HPA axis suppression, Cushing's syndrome, hyperglycemia, glucosuria, or irritation occurs. Occlude only if necessary; do not occlude higher ...

Because transdermal estrogen seems not to affect cortisol levels, there appears no need to discontinue therapy in the weeks before assessing the HPA axis, which is the procedure currently used for ...