An increasing number of HLA associations have been observed with drug-hypersensitivity reactions and it is crucial to understand the mechanisms involved in these reactions for both prognosis and ...

Aly et al. [17] provided evidence that risk for islet autoimmunity drastically increased in DR3/4-DQ2/DQ8 siblings who shared both HLA haplotypes identical by descent with their diabetic proband ...

The Australian Patent Office has granted a patent protecting a novel immunotherapeutic composition developed by Diamyd Medical for use in the treatment and prevention of autoimmune diabetes. The paten ...