Benjamin K. Chen, MD, PhD, discussed the next steps after the results of his study in genetic tagging showed promise in ...

Seven of the patients (10%) were found to have detectable HIV RNA in the CSF (median, 121; range, 52–860 copies/mL). These patients differed significantly from those without detectable CSF HIV ...

Because of improvements in the sensitivity of viral-load assays, it is now possible to detect HIV RNA levels below 50 copies/mL. However, in patients on antiretroviral therapy (ART), the clinical ...

To study pathogenesis and develop vaccines, it would be desirable to use infectious HIV and SIV clones derived from plasma viral RNA, which is more representative of the replicating virus pool ...

Because RNAs are so central to our biology, they are also drivers of a wide array of diseases. Defects in how RNA is produced ...

They graphically represent the life cycle of HIV-1, from the initial binding of ... cell's nucleus to spark the formation of new viral RNA strands (Viral Gene Transfer), and finally to the ...

Although DNA is the primary genetic material of cells, RNA is the genetic material for some viruses like HIV. A protein substance (immunoglobulin) produced by the immune system in response to a ...

In trials, 81% of participants taking the regimen achieved HIV RNA suppression, where levels of HIV were low enough to be considered undetectable after six months, with 83% showing continued ...

At 48 weeks, 98% of patients with HIV and initial viremia on long-acting ART achieved viral suppression, supporting updated ...

Furthermore, this method can be expanded to capture HIV RNA in the same cell. “ECCITE-seq allows us to tackle the heterogeneity, rarity and the lack of marker in these cells, which is very ...

A block to more potent and specific release of HIV from latency has been identified as a subunit of the Integrator complex, which may aid strategies for HIV cure.