One type of method executed in these regulated laboratories are HILIC methods which is used for separating polar compounds. HILIC methods present migration issues, especially for users who are not as ...

Two of the most common types of liquid chromatography include normal phase and reversed-phase chromatography, but now hydrophilic interaction chromatography (HILIC), which is a mixed-mode of ...

This is in contrast to the retention mechanism in HILIC, which relies on the partitioning of a compound between the aqueous surface layer of the hydrophilic stationary phase and the organic ...

The solution may be a label-free method that combines hydrophilic interaction liquid chromatography with mass spectrometry (HILIC-MS). This lets free thiols in mAb processing be localized directly ...

A Step-by-Step Approach for Method Development to Generate a Successful HILIC Separation Hydrophilic interaction liquid chromatography (HILIC) separations are gaining increased prominence in many ...

The chemical composition of the stationary phase in HILIC is often more complex than traditional high-performance liquid chromatography (HPLC) and uses a combination of different molecules that ...

Keep learning. Excel in your career. Choose from more than 200 courses in seven different categories, taught by experts in the chemistry community, online and in person.

Keep learning. Excel in your career. Choose from more than 200 courses in seven different categories, taught by experts in the chemistry community, online and in person.