Finally, the genes that were tagged by H3K27ac in metastases of human prostate cancer were expressed to a higher degree in embryonic mouse prostate tissues than they were in the postnatal prostate.

Phase II trial of intravesical camrelizumab in BCG-unresponsive high-risk non-muscle invasive bladder cancer. This is an ASCO Meeting Abstract from the 2024 ASCO Annual Meeting I. This abstract does ...

Combined high-resolution H3K27ac epigenomic and single-cell transcriptional profiling as a signature predictive of response to neoadjuvant immune checkpoint inhibitors (ICI) in urothelial cancer (UC).

Cancer can’t live without transcribing its favorite oncogenes ... or to recognition of post-translational modifications (“epi-marks” like H3K27ac), our lab is intrigued to investigate how these ...