Gout can cause serious pain in your big toe, or in other joints, and it can last for days. Learn more about this condition and what causes it.

A tophus can occur when you have gout and uric acid builds up around your joints. Larger tophi need to be removed so they don’t cause long-term damage.

Medically reviewed by Marissa Sansone, MD Medically reviewed by Marissa Sansone, MD Tophi are firm, painless yellow lesions that form in and around the joints in people with advanced gout. They ...

The duration of gout (11.80 vs 9.13 years; P =.001) and tophi (5.44 vs 3.55 years; P <.001) were longer among patients with vs without bone erosion, respectively.

Despite outdated misconceptions, gout is still very much a current health concern that affects millions of Americans. ... Tophi can deform joints and cause lasting damage to bones and tissues.

The European Alliance of Associations for Rheumatology - recommends that serum urate should be maintained at <6 mg/dL ...

Gout flares are associated with cardiovascular events. Treating gout to target serum urate levels prevents flares, but ...

This study demonstrates that gout patients from the US and three EU countries suffer from significantly decreased HRQOL, with the average patient suffering decreased mental as well as physical ...

Background Although typically a late feature of gout, tophi may present early in the course of disease. The aim of this study was to identify factors associated with the presence of early ...

If the levels continue to be high, or a person is unable to manage the condition, it can lead to gout. Tophus Related News | High Uric Acid: Symptoms You May Get In Your Feet At Night.