Although gout is no longer caricatured as a comical disease caused by high living and swilling port wine, it is still regarded as an affliction almost exclusively of adult men, many of whom like ...

Insulin resistance is another feature of metabolic syndrome and this can lead to increased uric acid levels. Metabolic syndrome is characterised by high blood pressure, high blood sugar, excess ...

gout appears to involve intricate interactions between genetics, metabolism, and the immune system. This more nuanced understanding could lead to more personalized approaches to gout treatment ...

Some 25 or 30 per cent of patients with primary gout are habitual overexcretors ... in-aid from the National Institute of Arthritis and Metabolic Diseases, National Institutes of Health, United ...

Originally designed as glucose-lowering medications, SGLT2 inhibitors provide benefits across the cardio-renal-metabolic ...

“We know that a higher BMI and obesity is associated with diabetes and is strongly associated with gout.” Additionally, metabolic syndrome is also common with these two conditions. Metabolic ...

Comorbidity-related risk factors for gout include excess alcohol consumption, dietary excess, CKD, metabolic syndrome and use of thiazide and loop diuretics. An important aspect of primary care is ...

The metabolism of uric acid is an essential facet of purine degradation, with significant implications for human health. In most mammals, uricase converts uric acid into allantoin, which is ...

Genetic predisposition to gout, unfavorable lifestyle habits, and poor metabolic health are associated with an increased risk for cardiovascular disease (CVD); however, adherence to a healthy ...

THE metabolism of uric acid in man, with special reference to its presumptive aberrations in gout, has been the subject of several excellent reviews in recent years, notably those of Seegmiller et al.