A glycan microarray is a high-throughput tool for investigating the binding between glycans – polysaccharides or carbohydrates, such as heparan sulfate (HS) and chondroitin sulfate (CS) – and ...

Sugars were considered so irrelevant, says Massachusetts Institute of Technology researcher Ram Sasisekharan, that biochemists "mainly developed tools to remove them from proteins they were ...

WT RBD recognizes ABO antigens differently; nevertheless, a glycan-based microarray loaded with multiple types of ABO antigens was investigated for direct comparison of the RBD's glycan binding ...

More information: Self-regulation of MGAT4A and MGAT4B activity toward glycoproteins through interaction of lectin domain with their own N-glycans, iScience (2024). DOI: 10.1016/j.isci.2024.111066 ...

Every organism has an associated glycome, a unique profile of associated carbohydrates also known as sugar chains or glycans. Glycomics, the study of individual glycomes, may lead to the ...

A group from Nagoya University in Japan has developed a simple, accurate, and sensitive method for measuring polysialic acid, a unique glycan found in the brain that fluctuates in the blood of ...

A group from Nagoya University in Japan has developed a simple, accurate, and sensitive method for measuring polysialic acid, a unique acidic glycan found in the brain. Polysialic acid fluctuates ...

Researchers cloned, purified and subjected COVID-19 receptor-binding domains and galectins to glycan microarray or flow cytometric analysis. Findings ...

Researchers have identified a new complex-carbohydrate biomolecule, or glycan, that plays a key role in the nasal colonization of the Bordetella bacteria responsible for whooping cough.