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The NNC2215 molecule consists of two major parts in its structure, a ring-shaped structure called a macrocycle and a modified glucose molecule called glucoside.
Bioengineers and scientists at Danish pharmaceutical company Novo Nordisk have synthesised an insulin molecule with an “on-and-off switch” that automatically responds to sugar levels in the blood.
b, Hoeg-Jensen et al. 3 designed a glucose-sensitive insulin called NNC2215, consisting of an insulin backbone, a glucose-binding macrocycle (ring-shaped molecule) and a glucoside (glucose-derived ...
Rita Slaaby, a principal scientist at pharmaceutical company Novo Nordisk in Bagsværd, Denmark, and her colleagues engineered an insulin molecule with a switch that turns its activity on and off ...
The compound reacts via a glycosylation reaction, where the OH is deprotonated and a glucose molecule adds to the O-. The new oxybenzone glucoside conjugate can still absorb light, but now does ...
According to the Merck Index, hyaluronic acid (HA; sometimes called hyaluronan) is “a natural high-viscosity mucopolysaccharide”.As shown in the images, it consists of repeating two-glucoside units.