Researchers studying over 2,000 Ashkenazi Jewish centenarians uncovered two rare IGF-1 gene variants linked to exceptional ...

1 The availability of validated, normative IGF-I data for age is also essential. Studies of GH therapy in children with ISS must be interpreted within the context of clinical and biochemical ...

Short-term GHRT was effective and safe without increased risk for cancers among real-world adults with growth hormone deficiency.

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This interaction results in intracellular signal transduction and subsequent induction of transcription and translation of GH-dependent proteins including IGF-1, IGF BP-3 and acid-labile subunit.