Erik Garrison using vg software (Wellcome Trust Sanger Institute) The genome graph is only just starting to crack open its cocoon. Paten and his colleagues hope to release the first open-access ...

To illustrate why graphs are useful for genome assembly, consider a simple example with five very short reads (CGTGCAA, ATGGCGT, CAATGGC, GGCGTGC and TGCAATG) sequenced from a small circular ...

We describe a new ancestral recombination graph inference algorithm that scales to large genome-wide datasets and demonstrate its accuracy on real and simulated data. We then generate a genome ...

(b) Schematic diagram of pan-genome graph showing relationship between a segment of the M. floribunda genome and the reference Fuji genome. Credit must be given to the creator. Only noncommercial ...

Instead of relying on a single reference genome, the scientists created a genome graph that combines all 30 species. This gave them a much clearer picture of how the genomes differ, especially in ...

Pan-genomic analyses combine the genomic information from a closely related group to understand evolutionary conservation and divergences and were greatly facilitated by the pan-genome graph tool.

Pan-genomic analyses combine the genomic information from a closely related group to understand evolutionary conservation and divergences and were greatly facilitated by the pan-genome graph tool.

Darryl Leja/NHGRI Supported by By Elie Dolgin More than 20 years after scientists first released a draft sequence of the human genome, the book of life has been given a long-overdue rewrite.