Historically, GP38 has been considered an important target for vaccines or other treatments. However, the lack of knowledge regarding GP38's function during infection has hindered efforts to ...

This recent publication showed that non-neutralizing GP38-specific mAbs targeting the N-terminal region of GP38 (region 2) were the most protective against lethal challenge, the most potent at ...

Treating mice with anti-GP38 antibodies reduced the amount of vascular leakage and levels of GP38 in the blood and prevented CCHFV from spreading into new tissues, the team found. “This study ...